Project members

We are committed to providing innovative treatments to patients through iPS cell technology.

At T-CiRA, several novel research projects focusing on the creation of medical applications of iPSC are underway, led by nine principal investigators (PI) with Co-principal investigators (Co-PI) from Takeda.

Cell Therapy

Development of a novel immunotherapy using iPSC-derived immune cells

Shin Kaneko（PI, CiRA）
Akira Hayashi（Co-PI, Takeda）
Yoshiaki Kassai（Co-PI, Takeda）
Shoichi Iriguchi（Sub PI, CiRA）
Keiko Koga（Sub PI, Takeda）

Research on Cell Therapy against Type 1 Diabetes

Taro Toyoda (PI, CiRA)
Ryo Ito(Co-PI, Takeda)
Shuhei Konagaya（Sub PI, CiRA）
Yutaka Tanoue（Sub PI, Takeda）
Hikaru Ueno（Sub PI, Takeda）
Noriko Yamazoe（SubPI, Takeda）

Development of an iPSC-derived cardiomyocyte cell therapy for severe heart failure

Yoshinori Yoshida (PI, CiRA)
Tomoyuki Nishimoto (Co-PI, Takeda)
Norihisa Tamura（Sub PI, Takeda）
Yasuharu Kamachi（Sub PI, Takeda）

創薬

ALS/ASD drug discovery and development using patient derived iPSCs

Haruhisa Inoue (PI, CiRA)
Hiroshi Yukitake (Co-PI, Takeda)
Inigo Narvaiza（Sub PI, Takeda）
Keisuke Shibata（Sub PI, Takeda）

Drug discovery for intractable muscular disease using patient-derived iPSCs

Hidetoshi Sakurai (PI, CiRA)
Ryuichi Tozawa (Co-PI, Takeda)
Tomoya Uchimura（Sub PI, CiRA）
Masahiro OKa（Sub PI, Takeda）
Tatsuo Oikawa（Sub PI, Takeda）

Development of therapeutic agents for rare hereditary diseases using iPS cells

Tadashi Suzuki (PI, RIKEN)
Ryuichi Tozawa（Co-PI, Takeda）
Hiroto Hirayama（Sub PI, RIKEN）
Takayuki Kamei（Sub PI, Takeda）

Living with NGLY1 deficiency: Grace’s Story

Drug discovery for genetic cardiac disease using a novel iPSC-based platform

Yoshinori Yoshida（PI, CiRA）
Tomoyuki Nishimoto（Co-PI, Takeda）
Kenichi Imahashi（Co-PI, Takeda）
Misato Koakutsu（Sub PI, CiRA）
Kohei Deguchi（Sub PI, Takeda）

Platform Technology

A new research platform with human iPSC-derived neural crest cells and its applications for drug discovery and regenerative medicine

Makoto Ikeya (PI, CiRA)
Hirokazu Matsumoto (Co PI, Takeda)
Daisuke Kamiya (Sub PI, CiRA)
Yayoi Toyooka (Sub PI, CiRA)
Teruyoshi Yamashita (Sub PI, Takeda)

Miniature liver technology as a platform for research towards pharmaceutical applications

Takanori Takebe (PI, TMDU)
Yasunori Nio（Co-PI, Takeda）

Development of novel gene therapy for Duchenne muscular dystrophy, by using genome editing and delivery technologies

Akitsu Hotta (PI, CiRA)
Naoto Inukai (Co-PI, Takeda)
Eriya Kenjo（Sub PI, Takeda）
Hiroyuki Hozumi（Sub PI, Takeda）

・Recruiting (CiRA) 

・Recruiting (Takeda) 

プロジェクト詳細