Update on Construction of New Plasma-Derived Therapies Manufacturing Facility in Juso, Osaka | Takeda Pharmaceuticals
Update on Construction of New Plasma-Derived Therapies Manufacturing Facility in Juso, Osaka
Osaka, JAPAN, September 30, 2025 – Takeda (TSE:4502/NYSE:TAK) today reaffirmed its commitment to expand its manufacturing capacity for plasma-derived therapies (PDTs) in Juso, Osaka, and provided an update on project planning as the company continues to respond proactively to changing market conditions.
Since announcing the project in March 2023, Takeda, together with a leading general contractor as its prospective partner, has made considerable progress working through the phases of conceptual, basic, and detailed design in line with disclosed plans. Informed by factors such as the depreciation of the yen, substantial rises in construction material costs, and ongoing labor shortages in the construction sector in Japan, Takeda reported in its Semi-annual Securities Report and Annual Securities Report of fiscal year 2024 an upward revision of the total investment to 153 billion yen, with an updated construction start in fiscal year 2025 and targeted completion in fiscal year 2029.
Following a recent comprehensive review of construction costs with our partners, Takeda has observed additional upward pressures on project costs. To ensure that our investment delivers enduring benefits for patients and the healthcare system in Japan and worldwide, Takeda will reevaluate the scope of the construction plan, as well as the timeline for both the commencement and the completion of the construction.
Takeda remains fully committed to people who rely on plasma-derived therapies. This reevaluation is part of our responsibility to enable the long-term success and sustainability of this investment. Our intent is to strengthen plans to ensure a robust and stable supply of these vital treatments to all patients in Japan and worldwide, contributing to better health and a brighter future for people around the world.
We will provide further updates as appropriate, in a timely and suitable manner should there be any relevant developments.
About Takeda
Takeda is focused on creating better health for people and a brighter future for the world. We aim to discover and deliver life-transforming treatments in our core therapeutic and business areas, including gastrointestinal and inflammation, rare diseases, plasma-derived therapies, oncology, neuroscience and vaccines. Together with our partners, we aim to improve the patient experience and advance a new frontier of treatment options through our dynamic and diverse pipeline. As a leading values-based, R&D-driven biopharmaceutical company headquartered in Japan, we are guided by our commitment to patients, our people and the planet. Our employees in approximately 80 countries and regions are driven by our purpose and are grounded in the values that have defined us for more than two centuries. For more information, visit www.takeda.com.
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