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<p>Earnings announcement for the 3rd quarter FY2022 (Feb 2, 2023)</p>


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<h4><a href="https://www.takeda.com/investors/financial-results/">Earnings announcement for the 3rd quarter FY2022 (February 2, 2023<span class="chevron-after" style="position: relative;">)</span></a></h4>
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<h4><span class="chevron-after" style="position: relative;"><a href="https://www.takeda.com/investors/ir-events/">41<sup>st</sup> Annual J.P. Morgan Healthcare Conference (4:30pm &ndash; 5:10pm PST on January 9, 2023)</a></span></h4>
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<h4><span class="chevron-after" style="position: relative;"><a href="https://www.takeda.com/investors/shareholders-meetings/">146th Ordinary General Meeting of Shareholders (June 29, 2022)</a></span></h4>
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<h4><span class="chevron-after" style="position: relative;"><a href="https://www.natpara.com/recall#/latest-updates">Information for US Patients Regarding the NATPARA Recall in the US</a></span></h4>
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<h4><span class="chevron-after" style="position: relative;"><a href="https://www.takeda.com/investors/stock-and-shares/procedure/">ADS Helpline</a></span></h4>
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<p style="text-align: right;">Takeda's focus on health equity; Rare Disease Day 2023</p>


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Takeda Statement Regarding Press Reports

<p>Takeda Pharmaceutical Company Limited (‘Takeda”) notes media speculation that it will make a firm offer for Shire plc (“Shire”). Takeda and Shire continue discussions regarding a possible offer.</p>
<p>Takeda will make an announcement if Takeda makes a firm offer and reaches any agreement in due course.</p>

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