Shire to participate at the Jefferies 2015 Global Healthcare Conference

June 1, 2015

Shire plc (LSE: SHP, NASDAQ: SHPG) announces that it will be participating in the Jefferies 2015 Global Healthcare Conference in New York, NY on Tuesday, June 2, 2015. Jeff Poulton, Chief Financial Officer will participate in a question and answer session at 10:00 a.m. ET (3:00 p.m. BST).

A live audio webcast will be available on the Presentations and Webcasts section of Shire's Investor website at http://investors.shire.com/presentations-and-webcasts/year-2015.aspx. Subsequently, a replay of the webcast will be available on this same website for approximately 90 days.

For further information please contact:

Investor Relations

   
Sarah Elton-Farr seltonfarr@shire.com +44 1256 894157

NOTES TO EDITORS

Shire enables people with life-altering conditions to lead better lives.

Our strategy is to focus on developing and marketing innovative specialty medicines to meet significant unmet patient needs.

We focus on providing treatments in Rare Diseases, Neuroscience, Gastrointestinal and Internal Medicine and we are developing treatments for symptomatic conditions treated by specialist physicians in other targeted therapeutic areas, such as Ophthalmics.

www.shire.com