Enable Accessibility Enable Accessibility

Director/PDMR Share Dealings

March 31, 2015

Shire plc (LSE: SHP, NASDAQ: SHPG) (the “Company”) announces that Ordinary Shares (“Shares”) and American Depositary Shares (“ADSs”) of the Company, as set out below, have been acquired today for the Non-Executive Directors, being the part of their total fees that are paid in shares for the period of service from January 1 to March 31, 2015.

  Type of Security (1) Number of Shares/ADSs
Dominic Blakemore Shares 100
William Burns Shares 118
Dr. Steven Gillis ADSs 41
Dr. David Ginsburg ADSs 35
David Kappler Shares 118
Susan Kilsby ADSs 125
Anne Minto Shares 121
David Stout ADSs 36

 (1)    One ADS is equal to three Shares

The Shares and ADSs were acquired on the London Stock Exchange and NASDAQ respectively at £54.3489 per Share and $237.20 per ADS.

This notification relates to disclosures made in accordance with 3.1.4(R)(1)(a) of the Disclosure and Transparency Rules.

Tony Guthrie
Deputy Company Secretary

For further information please contact:

Investor Relations

Sarah Elton-Farr
seltonfarr@shire.com
+44 1256 894157

NOTES TO EDITORS

Shire enables people with life-altering conditions to lead better lives.

Our strategy is to focus on developing and marketing innovative specialty medicines to meet significant unmet patient needs.

We focus on providing treatments in Rare Diseases, Neuroscience, Gastrointestinal and Internal Medicine and we are developing treatments for symptomatic conditions treated by specialist physicians in other targeted therapeutic areas, such as Ophthalmics.

www.shire.com

Click here for the PDF version of this press release.