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Director/PDMR Share Dealings

March 31, 2014

Shire plc (LSE: SHP, NASDAQ: SHPG) (the “Company”) announces that today Ordinary Shares (“Shares”) and American Depository Shares (“ADSs”) of the Company, as set out below, have been acquired for the Non-Executive Directors, being the part of their total fees that are paid in securities for the period of service from January 1 to March 31, 2014.


   Type of Security (1) Number of Securities
 Dominic Blakemore  Shares  147
 William Burns  Shares  178
 Dr. Steven Gillis  ADSs  57
 Dr. David Ginsburg  ADSs  54
 David Kappler  Shares  186
 Susan Kilsby  ADSs  61
 Anne Minto  Shares  185
 David Stout  ADSs  59


 (1)   One ADS is equal to three Shares

The Shares and ADSs were acquired on the London Stock Exchange and NASDAQ respectively at prices of £29.9876 per Share and $147.90 per ADS.

This notification relates to disclosures made in accordance with 3.1.4(R)(1)(a) of the Disclosure and Transparency Rules.

Tony Guthrie

Deputy Company Secretary

For further information please contact:

Investor Relations        

Laurie Stelzer   
[email protected]
+1 781 482 0733

Eric Rojas   
[email protected]
+1 781 482 0999

Sarah Elton-Farr   
[email protected]
+44 1256 894157

Notes to editors

Shire enables people with life-altering conditions to lead better lives.

Our strategy is to focus on developing and marketing innovative specialty medicines to meet significant unmet patient needs.

We provide treatments in Neuroscience, Rare Diseases, Gastrointestinal and Internal Medicine and we are developing treatments for symptomatic conditions treated by specialist physicians in other targeted therapeutic areas.


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