Transaction In Own Shares

Shire plc (LSE: SHP, NASDAQ: SHPG) (the “Company”) announces that, in accordance with the authority granted by shareholders at the Company's Annual General Meeting on April 30, 2013, it purchased 67,950 of its ordinary shares of 5 pence each (“Ordinary Shares”) on June 25, 2013 through both direct purchases of Ordinary Shares, and through the purchase of Ordinary Shares underlying ADRs. The highest and lowest price paid for the directly acquired Ordinary Shares was 2014.00 pence per share and 1992.00 pence per share respectively, and for those Ordinary Shares acquired though the purchase of ADRs was 3127.00 cents per share and 3103.00 cents per share respectively.

The purchased shares will be held as treasury shares. Following the above purchase, the Company holds 9,382,499 Ordinary Shares as treasury shares and has 553,467,199 Ordinary Shares in issue (excluding treasury shares).

The purchases were made by an independent third party which makes its trading decisions independently of, and uninfluenced by, the Company.  The independence of the third party enables the Company to continue to purchase Ordinary Shares (including Ordinary Shares underlying ADRs) during close periods and other prohibited periods, should they arise. The third party has been appointed by the Company to make purchases to December 31, 2013.

For further information please contact:

Investor Relations      

Eric Rojas  
[email protected]
+1 781 482 0999

Sarah Elton-Farr   
[email protected]
+44 1256 894157

NOTES TO EDITORS

Shire enables people with life-altering conditions to lead better lives.

Our strategy is to focus on developing and marketing innovative specialty medicines to meet significant unmet patient needs.

We provide treatments in Neuroscience, Rare Diseases, Gastrointestinal, Internal Medicine and Regenerative Medicine and we are developing treatments for symptomatic conditions treated by specialist physicians in other targeted therapeutic areas.

Click here for the PDF version of this press release.