The research publication of the development of therapeutics for NGLY1 deficiency in T-CiRA Joint Program were published online in Human Molecular Genetics on April 7^th ,2020.

The research publication of the development of therapeutics for NGLY1 deficiency in T-CiRA Joint Program were published online in Human Molecular Genetics on April 7^th, 2020.

https://academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddaa059/5817124?guestAccessKey=a99601eb-7468-4237-8173-5b4a108a64d5

Paper Details

• Journal: Human Molecular Genetics
• Title: Ngly1−/− rats develop neurodegenerative phenotypes and pathological abnormalities in their peripheral and central nervous systems
• Authors: Makoto Asahina^1,3, Reiko Fujinawa^1,2, Sayuri Nakamura⁴, Kotaro Yokoyama⁴, Ryuichi Tozawa^1,3, and Tadashi Suzuki^1,2
• Author Affiliations:

¹ Takeda-CiRA Joint Program (T-CiRA), 2518555 Kanagawa, Japan,

² Glycometabolic Biochemistry Laboratory, RIKEN Cluster for Pioneering Research, RIKEN, 3510198 Saitama, Japan,

³ T-CiRA Discovery, Takeda Pharmaceutical Company Ltd., 2518555 Kanagawa, Japan

⁴ Nonclinical Safety Research, Axcelead Drug Discovery Partners Inc., 2510012 Kanagawa, Japan.