Transaction In Own Shares

November 20, 2012

Shire plc (the “Company”) (LSE: SHP, NASDAQ: SHPG), announces that in accordance with the authority granted by shareholders at the Company's Annual General Meeting on April 24, 2012 it purchased 106,000 of its ordinary shares of 5 pence each on November 20, 2012. The highest and lowest price paid was 1760.00 pence per share and 1726.60 pence per share respectively.

The purchased shares will be held as treasury shares. Following the above purchase, the Company holds 1,579,134 shares as treasury shares and has 560,961,753 shares in issue (excluding treasury shares).

For further information please contact:

Investor Relations        

Eric Rojas   
erojas@shire.com
+1 781 482 0999

Sarah Elton-Farr   
seltonfarr@shire.com
+44 1256 894157

Notes to editors

Shire enables people with life-altering conditions to lead better lives.

Through our deep understanding of patients’ needs, we develop and provide healthcare in the areas of:

  • Behavioral Health and Gastro Intestinal conditions
  • Rare Diseases
  • Regenerative Medicine

as well as other symptomatic conditions treated by specialist physicians.

We aspire to imagine and lead the future of healthcare, creating value for patients, physicians, policymakers, payors and our shareholders.