Enable AccessibilityEnable Accessibility

Director/PDMR Shareholding

November 7, 2011

Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company was notified today that on November 4, 2011, Sylvie Gregoire exercised SAR Awards granted under the Shire Portfolio Share Plan over Shire American Depository Shares (“ADSs”) and sold the resulting ADSs.

Number of
ADSs exercised
Number of
ADSs released
Number of
ADSs sold
13,000 $73.62 3,107 3,107 $96.7509
4,000 $58.90 1,564 1,564 $96.7509

One ADS is equal to three Shire ordinary shares.

This notification relates to disclosures made in accordance with 3.1.4(R)(1)(a) of the Disclosure and Transparency Rules.

Tony Guthrie
Deputy Company Secretary


For further information please contact:

Investor Relations Eric Rojas ([email protected]) +1 781 482 0999
  Sarah Elton-Farr ([email protected]) +44 1256 894157


Notes to editors


Shire’s strategic goal is to become the leading specialty biopharmaceutical company that focuses on meeting the needs of the specialist physician.  Shire focuses its business on attention deficit hyperactivity disorder, human genetic therapies, gastrointestinal diseases and regenerative medicine as well as opportunities in other therapeutic areas to the extent they arise through acquisitions.  Shire’s in-licensing, merger and acquisition efforts are focused on products in specialist markets with strong intellectual property protection and global rights.  Shire believes that a carefully selected and balanced portfolio of products with strategically aligned and relatively small-scale sales forces will deliver strong results.

For further information on Shire, please visit the Company’s website: www.shire.com.