Oncology |
REF#5Platform technologies for immuno-oncology drug discovery and translational research The following topics will be prioritized:
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Gastroenterology |
REF#6Base editing for liver diseases Base editing approaches enabling in vivo editing of disease-causing mutations in DNA are envisioned. Novel editing enzymes with potential to be developed as mRNA/LNP formulations for delivery to hepatocytes are desired.
REF#7Intestinal cell (i.e. fibroblast, macrophage) delivery platform Technologies that allow for selective delivery of anti-fibrotic agents (e.g. proteins, small molecules, oligos) to activated fibroblasts and macrophages within the fibrotic intestinal tissue of fibrostenotic Crohn’s disease are envisioned. Approaches that avoid accumulation in other organs are highly desirable
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Medicinal chemistry and DMPK |
REF#8Novel technologies for nucleic acid drug development Chemistry-driven technologies focusing on the following topics will be prioritized
REF#9Novel technologies, methods or approaches to accelerate drug discovery process The following topics will be prioritized:
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