Oncology

#13

Development of CAR-engineered T cell products against novel solid and/or hematological malignancies targets

Chimeric antigen receptor engineered T cells (CAR-T cells) have made remarkable strides in the treatment of patients with B cell malignancies exemplified by anti-CD19 CAR-T cells in B cell acute lymphoblastic leukemia (B-ALL.). This success however has encountered hurdles in translation across hematological malignancies and even more so in solid tumors.
We welcome proposals aimed at the development of novel CAR-engineered T cell products against solid and/or hematological malignancies. Proposals aimed at overcoming limitations such as tumor selective expression, heterogeneous antigen expression, immunosuppressive networks in the tumor microenvironment, optimal CAR construct, T cell function and persistence, and inadequate trafficking are desired.



#14

Research and development toward realization of innovative technology for next generation cellular cancer immuno-therapy

Along with the recent remarkable changes in modality for cancer therapy, like immuno-checkpoint inhibitors and CAR-T cells, other cancer immuno-therapy which is completely different from the traditional cancer therapies has been actively developed. In this subject, we are looking for innovative ideas and related technologies for cancer immuno-therapy applicable to cell therapy. As CAR-T cells are covered in subject 13, so we are seeking new proposals that are not related to CAR-T cells and will lead to differentiation from existing cancer therapies.



Other Areas of Interest




How to Apply

Follow the procedure below to make an application.

  1. Download the Proposal Sheet below, and complete based on the non-confidential information.

  2. Click "SUBMIT". To proceed with the application you must agree with the Terms and Conditions that are presented to you. Once you have agreed with them, click “I ACCEPT”.

  3. Complete the Application Form with your Proposal Sheet prepared at Step1 attached, and click "SUBMIT".

  4.  After submission, your website will show the “Submission Completed” page and you will receive a confirmation email.

CONTACT

Please contact the COCKPI-T® Funding Office for further information.

COCKPI-T@takeda.co.jp

  

* Please be aware that we may not be able to respond to every inquiry.