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Natural Resource Conservation


As part of our commitment to environmental stewardship, we have established new goals related to water and waste management practices. The new goals will help focus our efforts on these important environmental challenges.


Water scarcity and quality issues are global concerns; however, the challenges regarding water must be managed at the local level. At Takeda, we’re working to understand our water impacts across our company, site by site, so that we can focus our efforts at the locations where we can make the most meaningful difference. Understanding our water impact goes beyond measuring water consumption and includes assessing local water risk — looking at factors such as access to water challenges, regulations, biodiversity, future demand and seasonal fluctuations in water availability.

Currently, we assess local water risks using the World Resources Institute Aqueduct and WWF Water Risk Filter Tools, which indicate that approximately 22% of our manufacturing sites are located in areas considered to have “high” or “extremely high” water risk. Remaining manufacturing sites are in areas considered to have “low” to “medium” water risk. This mapping process will help us target and prioritize our efforts.

We have a long history of reducing water consumption in our manufacturing facilities by investing in water-efficient equipment and processes, as well as by maximizing water reuse where possible. These initiatives will continue as we pursue our environmental sustainability goals. Since the processing of water requires significant amounts of energy, many of these initiatives have the benefit of not just saving water, but also reducing energy and associated GHG emissions. We’re proud that, as a result of these efforts, we achieved our 2020 water stewardship goal ahead of schedule, allowing us to establish a new context-based water stewardship strategy, which includes the following long-term goals:

  • By FY2021, Takeda will establish mitigation plans, risk-reduction goals and water conservation goals for 100% of sites with high water-related risks.
  • By FY2025, Takeda will reduce water consumption by 5% from a FY2019 baseline.

In 2019, we withdrew 11,114 thousand cubic meters of fresh water and discharged 8,175 thousand cubic meters. Water consumption was due to inclusion in finished product, site cooling and irrigation purposes.

Wastewater and chemical substances

Takeda manages the quality of effluent wastewater in line with the following principles:

  • Prevent negative effects on people and the ecosystem.
  • Comply with applicable laws and regulations.
  • Manage wastewater proactively, based on scientific evidence, substance concentrations and environmental toxicity.

We handle a wide variety of chemical substances, including our pharmaceutical products, and we manage these substances in ways that minimize emissions in line with our policies. This includes better understanding and limiting the potential impact of APIs and the larger issue of Pharmaceuticals in the Environment (PiE) from our manufacturing and R&D operations.

We manage requirements for PiE in our manufacturing facilities through robust waste management and wastewater treatment processes, while complying with national, state and local discharge regulatory obligations. We partner with and communicate our EHS requirements to our contract management organizations (CMOs) to prevent the release of hazardous substances and byproducts into the environment. We comply with regulatory requirements to perform environmental risk assessments and toxicological and safety assessments to evaluate and build in environmental and patient safety as  part of our marketing authorization applications in the U.S. and internationally. We continually review regulatory requirements for products we manufacture internally and through CMOs, to minimize the impact on the environment.

In addition to proactive waste management and wastewater treatment processes, Takeda also collaborates to address PiE and antimicrobial resistance (AMR). For example, Takeda is part of the European Federation of Pharmaceutical Industries and Associations (EFPIA) consortium that is involved in developing a position and roadmap for addressing PiE at the industry level.

Additionally, due to the increasing number of bacteria that are resistant to antibiotics, Takeda is one of more than 20 leading biopharmaceutical companies that have launched the AMR Action Fund, a groundbreaking partnership that aims to bring two to four new antibiotics to patients 
by 2030. The Fund is working on two primary areas of focus:

  • Bolster and accelerate the research and development of antibiotics through investment and sharing of industry resources and knowledge with biotechnology companies.
  • Create a unique, collaborative platform with support from multilateral development banks, philanthropic funders, other impact funds and strategic partners to facilitate policy reforms to create an environment that encourages long-term investment into antibiotic R&D.

We work to reduce the amount of waste sent to landfill, first by limiting the amount of waste we generate and then by reusing what we can and recycling the rest. We’ve set a goal to achieve zero waste-to-landfill status for all major locations2 by 2030.

In 2019, Takeda generated 74,108 tonnes of waste, of which 71% was recycled. An additional 9% was diverted from landfill via incineration without energy recovery or via other treatment technologies.

Many of our sites have begun finding innovative solutions that not only reduce waste, but also help reduce energy and associated GHG emissions. For example, Takeda’s Thousand Oaks, California, U.S., site introduced the AeroSafe® 18L and 39L ISC shipping solutions, which are reusable while offering a simple pack-out and maintain temperatures between 2-8°C. With vacuum-insulated panels and phase-change material, they can be refrigerated to extend their life, making them a “green solution” that will help reduce our carbon footprint.

2 Major locations include manufacturing, R&D sites, BioLife plasma donation centers and major commercial office locations.

Brazil Plant Achieves 100% Zero-Waste-to-Landfill Designation

Takeda’s manufacturing facility in Jaguariúna, Brazil, has achieved 100% zero waste to landfill, including construction, demolition, organic and hazardous waste, but excluding general waste. The facility reached the milestone after working for over a year toward the goal.

1 Changes in FY2019 waste management percentages compared to past performance are attributed to the harmonization of waste tracking reporting practices after the integration of the Shire acquisition.

Environment, Health and Safety (EHS) Performance Data — FY2019

Category/Metric FY2019 Data1 KPMG Assured
Energy (Terajoules)    
    Purchased Electricity (Non-Renewable) 2,217  
    Purchased Electricity (Renewable)2 758  
    Onsite Generated Renewable Electricity 4  
Percent Electricity Sourced as Renewable3 26%  
Percent Electricity as Renewable Including Renewable Energy Certificates (RECs) 100%  
    Supplied Heating and Cooling 113  
    Fuel Consumption4 4,891  
Total Energy Consumption 7,983 X
Greenhouse Gas Emissions (Thousand MTCO2e)5    
    Scope 1 Emissions 333 X
    Scope 2 Emissions — location-based methodology 319 X
    Scope 2 Emissions — market-based methodology 248 X
    Scope 3, all applicable categories 3,943 X
Total GHG Emissions6 4,524  
Carbon Neutrality 2,324  
    Purchased Verified Emission Reductions (VERs) — Thousand MTCO2e7 4,308 X
    Purchased RECs — Terajoules 2,324 X
    Percent Reported GHG Emissions Mitigated by Purchased VERs and RECs 100%  
Air Emissions (Metric Tons)    
Sulphur Oxides (SOx) and Nitrous Oxides (NOx) Emissions8 110  
VOCs 130  
Water (Thousand Cubic Meters)    
Water Withdrawal 11,114 X
    Water Withdrawal in Areas with High or Extremely High Water Risk9 1,223 X
    Water Withdrawal in Areas with Medium-High Water Risk9 1,237 X
    Water Withdrawal in Areas with Low or Low-Medium Water Risk9 8,369 X
Wastewater Discharged 8,175  
Water Consumed10 2,939  
Quantity of Chemical Oxygen Demand (COD) Discharged - Metric Tons11 46  
Waste (Metric Tons)    
    Total Regulated Waste Generated 34,184 X
    Total Non-Hazardous Waste Generated 39,924 X
Total Waste Generated 74,108  
Percent Waste Recycled12 71% X
Percent Waste Sent to Landfill 20% X
Health & Safety Incident Rates (per 200,000 hours worked)    
    Total Recordable Incident Rate 0.92 X
    Incidents with Days Lost Rate 0.23 X
Significant Spills and Releases    
    Number of Notices of Violation or Citations Received 7  
    Total Number and Volume of Significant Spills 0  
  1. The scope of Takeda operations is as follows:
    - For total energy consumption, Scope 1 and Scope 2 market, and location-based GHG emissions, the scope of Takeda operations includes all manufacturing and R&D sites, United States and Austria plasma collection centers, Takeda headquarters and commercial office locations.
    - For all other environmental performance indicators, the scope of Takeda operations includes all manufacturing and R&D sites, United States and Austria plasma collection centers, and larger commercial offices where such data was available. Contributions from smaller commercial office locations are not included.
    - For Health & Safety performance indicators, the scope of Takeda operations includes all manufacturing and R&D sites, United States and Austria plasma collection centers, and commercial office locations, covering approximately 95% of all employees.
  2. Includes renewable electricity purchased through bundled guarantees of origin contracts. Excludes unbundled renewable energy purchased through renewable energy certificates.
  3. Excludes electricity produced onsite through combined heat and power or fuel cell systems, as well as purchased renewable energy certificates.
  4. Excludes the energy content of fuel used for commercial fleet vehicles. GHG emissions from commercial fleet vehicles are included in Scope 1 emissions. Calculated using the default heat content of the consumed fuels from the “Greenhouse Gas Inventory Guidance, Direct Emissions from Stationary Combustion Sources” (U.S. EPA, January 2016).
  5. Scope 1 emissions are calculated using the GHG emission factors from the GHG Protocol Emission Factors from Cross-Sector Tools (2017). Scope 2 location-based emissions from purchased electricity are calculated using the country-specific emission factors published by the IEA and U.S. EPA. Scope 2 market-based emissions from purchased electricity are calculated using the supplier-specific emission factors when available, and country-specific emission factors published by the IEA and U.S. EPA when not available. See page 99 for Scope 3 emissions calculation methodology per category.
  6. Total GHG emissions calculated using the Scope 2 market-based total.
  7. Purchased Verified Emission Reductions sufficient to cover Scope 1 and Scope 3 GHG emissions in addition to Scope 2 GHG emissions from supplied heating and cooling. Total GHG emissions mitigated is 4,283,098 MTCO2e.
  8. NOx and SOx emissions calculated based on fuel consumption data and emission factors from the U.S. EPA Publication “Compilation of Air Pollutant Emission Factors, AP-42, Fifth Edition, Volume 1: Stationary Point and Area Sources.”
  9. Overall water risk rating based on the World Resource Institute Aqueduct 3.0 tool. Overall water risk measures all water-related risks by aggregating all selected indicators from the Physical Risk Quantity, Physical Risk Quality, and Regulatory and Reputational Risk categories. Higher values indicate higher water risk.
  10. Water consumed represents the difference between water withdrawals and wastewater discharges.
  11. COD Emission data reflects COD loading associated with the direct discharge of Takeda-treated wastewater to a receiving waterway.
  12. Recycled includes materials sent offsite for processing prior to reuse, as well as materials sent offsite for incineration with energy recovery.