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Research Alliances

In recent years, pharmaceutical discovery has come to require a combination of technologies from a number of specialized fields. While continuing to improve its own R&D capabilities, Takeda actively pursues alliances with other pharmaceutical manufacturers, biotechnology companies, universities, and other research institutions to efficiently introduce key technologies.

Research Alliances with overseas research organizations and companies

Partners Research subject Schedule
Seattle Genetics
(U.S.)
Research collaboration on Antibody-Drug Conjugate
Mar 09-
Alnylam Pharmaceuticals, Inc.
(U.S.)
Alliance in RNAi therapeutics in the fields of oncology and metabolic disease with the option to expand to additional therapeutic areas. May 08- May 13
Archemix. Corp.
(U.S.)
Joint research on discovery and development of Aptamer therapeutics. Jun 07-
LG Life Sciences
(Korea)
Joint research on discovery, development commercialize anti- obesity drugs. Mar 07- Mar 11
XOMA Ltd.
(U.S.)
Joint research on discovery, development and production technologies of monoclonal antibody Nov 06-
Arius Research Inc.*
(Canada)
Joint research on functional antibodies in Cancer field Apr 06-
Paradigm Therapeutics
(UK)
Drug discovery alliance in CNS disease Jul 05- Jun 08
Lexicon Genetics Incorporated
(U.S.)
Joint research on drug target of hypertention Jul 04- Jul 07
Evotec NeuroSciences
(Germany)
Drug discovery alliance in Alzheimer's disease Aug 03- Jul 07
Beth Israel Deaconess Medical Center (Harvard Medical School)
(U.S.)
Joint research on drug discovery related to diabetes and obesity Jul 02-
Oxford Centre for Diabetes Endocrinology and Metabolism
(UK)
Partnership with Oxford Diabetes Centre Apr 02-
Gene Logic
(U.S.)
Data base of gene expression (extended target disease since Mar 03) Mar 02- Dec 06
Array BioPharma
(U.S.)
Joint research on lead compound synthesis Jul 01- Sep 05
Celera
(U.S.)
Joint research on human genome Mar 00- Feb 05
WHO
(Switzerland)
Joint research on antimalarial drug discovery Oct 99- Oct 04

[*]Roche and Arius Research Inc. announced that the two companies have signed a definitive agreement for Roche to acquire Arius on July 23, 2008.

Research Alliances with domestic research organizations and companies

Partners Research subject Schedule
Osaka University Development of novel diagnostics of lifestyle-related diseases by novel secretory factors Apr 04- Mar 07
Kyoto University Kyoto Cell / Biodynamic Simulation Oct 03- Mar 08
Kirin Brewery (Now Kyowa Hakko Kirin) Licensing-in of the human antibody technology Jul 03 -
Keio University Target discovery for molecules differentiating neuronal stem cells to neurons Apr 03- Mar 06
RIKEN (The Institute of Physical and Chemical Research) Analysis of SNPs related to pioglitazone-induced edema Feb 03- Mar 06
RIKEN (The Institute of Physical and Chemical Research) Research for human genome relating to osteoarthritis Jul 02- Mar 05
Keio University Research for human genome relating to hypertension and diabetic organopathy Mar 02- Feb 05
Shin Nippon Biomedical Laboratories Research for toxico-genomics Jan 02- Jan 06
Biomolecular Engineering Research Institute Research for application of biomolecular functions Jun 01- Mar 06
Kagoshima University Joint research on efficacy evaluation of anti-HIV drugs Oct 97- Mar 05

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