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Global Research & Development System
Takeda has research functions in Japan, the U.S., UK., and in Singapore. The global research infrastructures surely represents its initiatives for pursuing the world's highest standard of productivity and will support enhancement of its R&D pipeline as source for future growth.
At the Tsukuba laboratories, researchers discover the seeds of innovative pharmaceuticals, the first step in the creation of new drugs. They focus on genetic information as well as research on cell receptors and enzymes that are integrally related to the causes of disease. The center conducts research into orphan receptors and bioactive peptides, discovering seeds for various receptor antagonists and agonists. It is also engaged in cutting-edge research areas such as identification of disease-related genes, computer-based combinatorial chemistry, and drug design.

The Tsukuba Research Center
The laboratories in Osaka focus on Takeda's core therapeutic areas. The center creates, evaluates and screens massive numbers of new compounds and selects new drug candidate compounds from among these. It then tests these candidate compounds for efficacy, safety, pharmacokinetics, and metabolism. The center is also engaged in drug delivery system (DDS) technology.

The Osaka Research Center
TSD exploits its competitive advantage in high-throughput structural biology to be the first organization to determine the three dimensional structure of known drug targets. TSD uses these structures to drive iterative, structure-based drug design programs to efficiently generate potential drug candidates. Innovative science and technology that have developed by TSD can be a driving force in expediting the drug development process.

Takeda San Diego, Inc.
Takeda acquired Paradigm Therapeutics Limited as the research bases in the Europe and Asia.
The company and its subsidiary renamed Takeda Cambridge Limited, Takeda Singapore Pte Limited.

Takeda Cambridge Limited

Takeda Singapore Pte Limited
PhotoTo speedily deliver superior pharmaceutical products to people around the world, Takeda is building a clinical development network centered in Japan, the United States and Europe. In the United States, development activities are carried out by Takeda Global Research & Development Center Inc., and TAP Pharmaceutical Products Inc. In Europe, Takeda Global Research & Development Centre (Europe), Ltd. conducts development activities in cooperation with other European subsidiaries and affiliates. By strengthening and coordinating the cooperation among all of its clinical development bases, Takeda is actively responding to the move toward global standardization of clinical trial data, which is being promoted by the ICH (International Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use).
(See Clinical Study Protocol Summaries for details.)
(See Clinical Study Report Summaries for details.)