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December 25, 2008

Takeda Pharmaceutical Company Limited

Notice Concerning Cancellation of Own Shares

Osaka, Japan, December 25, 2008 --- Takeda Pharmaceutical Company Limited (“Takeda”) announced that its Board of Directors resolved today to cancel its own shares under Article 178 of the Corporation Law, as detailed below:

1. Class of shares to be cancelled: Shares of common stock
2. Aggregate number of shares to be cancelled: 25,486,300 shares
(The ratio to the aggregate number of issued shares before cancellation: 3.13%)
3. Scheduled cancellation date (Plan): January 16, 2009

( Reference )

Total number of issued shares after cancellation: 789,666,095 shares

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