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June 24, 2008

Takeda Pharmaceutical Company Limited

Notice Concerning Cancellation of Own Shares

Osaka, Japan, June 24, 2008 --- Takeda Pharmaceutical Company Limited (“Takeda”) announced that its Board of Directors resolved today to cancel its own shares under Article 178 of the Corporation Law, as detailed below:

1. Class of shares acquired: Shares of common stock
2. Aggregate number of shares to be cancelled: 16,990,000 shares
    (The ratio to the aggregate number of issued shares before cancellation: 2.04%)
3. Scheduled cancellation date (Estimate): July 18, 2008

( Reference )

Total number of issued shares after cancellation: 815,152,395 shares


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