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April 25, 2008

Takeda Pharmaceutical Company Limited

Notice of Execution of Acquisition of the Company’s Own Shares

Osaka, Japan, April 25, 2008 --- Takeda Pharmaceutical Company Limited (“Takeda”) announced today that it completed acquisition of its own shares in the market, which was resolved by its Board of Directors on April 10, 2008.

1. Class of shares acquired: Shares of common stock
2. Period of acquisition: From April 11, 2008 to April 24, 2008
3. Total number of shared acquired: 11,000,000 shares
4. Total value of acquisition: Yen 57,825,512,000
5. Method of acquisition: Purchased on the Tokyo Stock Exchange

(Reference)

Resolution of the Board of Directors on April 10, 2008

1. Class of shares to be acquired: Shares of common stock
2. Number of shares to be acquired: Up to 11 million shares
(equivalent to 1.24% of a total of issued shares)
3. Total amount of shares to be acquired: Up to 60 billion Yen
4. Schedule of acquisition: From April 11, 2008 to April 28, 2008

Treasury shares held by Takeda as of April 24, 2008

1. Aggregate number of issued shares:
   (excluding treasury shares)
831,943,046 shares
2. Number of treasury shares: 57,329,349 shares


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