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>Fundamental Policy

Takeda's management mission is to "strive towards better health for patients worldwide through leading innovation in medicine." In line with this mission, Takeda is working to establish a management framework befitting a world-class pharmaceutical company that operates globally. We are strengthening internal control, including rigorous compliance, and establishing a structure to facilitate rapid decision-making that is sound and transparent. Through these initiatives, we will further enhance our corporate governance, thereby maximizing corporate value.
At Takeda, the Board of Directors determines the fundamental policies for the Takeda Group. Management and business operations are then conducted in accordance with the decisions of the Board of Directors. Transparency of the Board of Directors is achieved through audits conducted by outside corporate auditors. At the same time, the Company also has non-executive directors to help ensure appropriate execution of business operations without excessive reliance on a pharmaceutical industry perspective. Moreover, as management tasks continue to diversify, the group has appointed special officers to ensure a flexible and swift response: the Chief Medical & Scientific Officer (CMSO), who is responsible for promoting innovation and increasing the productivity of R&D activities; and the Chief Commercial Officer (CCO), who manages all overseas sales and marketing functions, except in the area of oncology.
The Company has also established a Global Leadership Committee, composed mainly of internal directors, which responds to the global business risks that have accompanied expansion of the scope of business. Global Leadership Committee plays a role as a system for deliberating and decision making on the important issues facing the Takeda Group, from an optimal company-wide perspective.

Takeda has given its Board of Directors the primary functions of observing and overseeing business execution as well as decision-making for company management. The Board of Directors consists of nine directors, and meets once per month in principle to make resolutions and receive reports on important matters regarding management.
Furthermore, a Nomination Committee and a Compensation Committee have been established as advisory bodies to the Board of Directors. The committees are each chaired by a non-executive director. Together, the committees serve to ensure transparency and objectivity in decision-making processes and results relating to personnel matters for internal directors (appropriate standards and procedures for appointment and reappointment, and having and administering appropriate succession plans) and to the compensation system (appropriate levels of compensation for the directors, appropriate performance targets within the director bonus system, and appropriate bonuses based on business results).
Any risks we may face in the course of global business operations are managed by the personnel responsible for risk management in the key organizations within the relevant domain. We therefore have set a system in place to prevent or mitigate risks, according to their degree and nature.
Furthermore, based on the "Takeda Group's Management Policy" and the "Management Policy for Affiliated Companies," we work to clarify the roles and responsibilities of all Group companies. We ensure compliance and appropriate business operations through implementation of periodic internal audits and the Control Self Assessment (CSA) program*.
Takeda is a Company with Auditors as defined in Japan's Companies Act. Takeda has established a system to ensure the effective implementation of audits, under the "Audit Rules by Corporate Auditors" which prescribe the activities of auditors, including attendance at important meetings and authority to review important documents. To ensure greater transparency of management, Takeda has appointed two outside auditors (out of four auditors in total), who conduct effective audits from an external perspective. We therefore consider that we have ensured objective and impartial management oversight. In addition, KPMG AZSA & Co. serves as the accounting auditor.