Product Portfolio

Ethical drugs are Takeda's core business. Takeda provides ethical drugs across a range of therapeutic areas to meet the needs and expectations of medical professionals and patients around the world.
Our portfolio includes lansoprazole for the treatment of peptic ulcers, leuprolide acetate for the treatment of prostate cancer and endometriosis, pioglitazone hydrocholoride for the treatment of diabetes, and candesartan cilexetil for the treatment of hypertension.
These four drugs are designated as "international strategic products" and we are focusing on managing their product lifecycles to strengthen sales on a global level.

In addition, Takeda promotes enhancing R&D pipeline, while concentrating its management resources to the four core therapeutic areas: lifestyle-related diseases, oncology and urological diseases, central nervous system disease and gastroenterological diseases in order to provide new drugs to the patients who need them at the earliest possible date.

International Strategic Products (Ethical Drugs)

Pioglitazone Hydrochloride ( For diabetes )

Once-daily dosing with pioglitazone hydrochloride improves insulin sensitivity and reduces blood glucose levels, without placing any additional burdens on the pancreas. The drug is marketed in around 80 countries worldwide. In the United States, Actoplus Met, a fixed-dose combination tablet of pioglitazone hydrochloride and metformin, as well as Duetact, a fixed-dose combination tablet of pioglitazone hydrochloride and glimepirids, are also marketed.

Consolidated sales(FY2008)：¥387 billion

Brand Name: Actos (Japan, United States, Europe, Asia)

Candesartan Cilexetil ( For hypertension )

Candesartan cilexetil is an angiotensin II receptor blocker^[*] (ARB) that is revolutionizing hypertension treatment. In around 90 countries worldwide, candesartan cilexetil enjoys a trusted reputation in the medical profession, as its once-daily dosing provides patients with a mild anti-hypotensive action which is long-lasting. In addition, candesartan cilexetil is also has efficacy for the treatment of chronic heart failure.

[*] Angiotensin II receptor blocker: blocks the action of angiotensin II, a hormone that increases blood pressure.

Consolidated sales(FY2008)：¥230 billion

Brand Names: Blopress (Japan, Europe, Asia), Amias, Kenzen (Europe)

Lansoproazole ( For peptic ulcers )

Once-daily dosing with lansoprazole, a proton pump^[*] inhibitor, provides fast symptom relief for gastric and duodenal ulcers, and achieves high healing rates. Lansoprazole is marketed in around 90 countries worldwide and is recognized as the top brand in major countries.

[*] Proton pump: an enzyme that functions in the final stages of acid secretion in gastric parietal cells.

Consolidated sales(FY2008)：¥271 billion

Brand Names: Takepron (Japan, Asia), Prevacid (United States, Asia) Ogast, Lansox, Agopton (Europe)

Leuprorelin Acetate ( For prostate cancer and endometriosis )

Leuprorelin acetate is an LH-RH agonist with a sustained-release formulation whereby the result of the drug delivery system (DDS) was devoted. In March 2008, its sustained-release formulation, available up to once every six months, was also approved in France. Leuprorelin acetate is marketed in around 80 countries worldwide, and is considered a gold standard therapy for prostate cancer.

Consolidated sales(FY2008)：¥126 billion

Brand Names: Leuplin (Japan), Enantone/ Trenantone (Europe, Asia)